MUC1 ECTODOMAIN IS A FLAGELLIN-TARGETING DECOY RECEPTOR AND BIOMARKER OPERATIVE DURING PSEUDOMONAS AERUGINOSA LUNG INFECTION

MUC1 ectodomain is a flagellin-targeting decoy receptor and biomarker operative during Pseudomonas aeruginosa lung infection

Abstract We previously reported that flagellin-expressing Pseudomonas aeruginosa (Pa) provokes NEU1 sialidase-mediated MUC1 ectodomain (MUC1-ED) desialylation and MUC1-ED shedding from murine lungs in vivo.Here, we asked whether Pa in the lungs of patients with ventilator-associated pneumonia might also increase MUC1-ED shedding.The levels of MUC1-

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Cathepsin W, T-cell receptor-associated transmembrane adapter 1, lymphotactin and killer cell lectin like receptor K1 are sensitive and specific RNA biomarkers of canine epitheliotropic lymphoma

Cutaneous T-cell lymphoma (CTCL) is an uncommon type of lymphoma involving malignant skin-resident or skin-homing T cells.Canine epitheliotropic lymphoma (EL) is the most common form of CTCL in dogs, and it also spontaneously arises from T lymphocytes in the mucosa and skin.Clinically, it can be difficult to distinguish early-stage CTCLs apart from

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Senses and meanings of being a woman, black, poor and illiterate

This is an article that seeks to bring reports from the subject women of Youth and Adult Education (EJA), from a literacy class.The reports were collected in 2019 and are part of the records of the activities Bottoms - Shorts of the teacher of that class.EJA is characterized by the strong presence of women, especially in this class, they were women

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